BDBM50512334 CHEMBL4458344

SMILES CNc1cncc(n1)-c1c[nH]c2nc(Nc3ccc(cc3)N3CCOCC3)nc(O[C@@H]3CCCN(C3)C(=O)C=C)c12

InChI Key InChIKey=XTRQLWDUMOTTDA-OAQYLSRUSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50512334   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50512334(CHEMBL4458344)
Affinity DataIC50:  138nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR kinase domain (696 to end residues) expressed in baculovirus infected Sf21 insect cells us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed